Karipcin takes a holistic approach with her patients to help them achieve their goals of having a baby. Use our online form or call:. This means that males and females are equally affected. The spleen also suffers damage from the sickled cells blocking healthy oxygen carrying cells.
Many autosomal recessive conditions occur this way. Use our online form or call:. For more information please call our office at HOPE. Sinem Karipcin is a Board certified infertility specialist. Sickle cell is a disease that's primarily seen in people of African descent.
Examples of autosomal recessive disorders include cystic fibrosis, sickle cell anemia, and Tay-Sachs disease.
Sachs, who originally described this condition, noted that most Tay Sachs babies were usually of eastern European Jewish origin. Sickle cells only live for about 15 days, whereas normal hemoglobin cells can live up to days. Need assistance? And it is simply amazing to me that this all comes from one very small change, changes in amino acid, that really isn't having any effect on the normal function of the protein, but has big effects on all of the other systems in the body that the red cells pass through.
Anyone can carry virtually any type of recessive gene; however, there may be certain ethnic groups more likely to carry certain recessive genes, because of where the mutation originated. Sickle cell hemoglobin cells are stiff and sticky, and form into the shape of a sickle, or the letter "C" when they lose their oxygen.
This population is from eastern Europe, where experts believe the mutation originated. Karipcin takes a holistic approach with her patients to help them achieve their goals of having a baby. Sickle cells are stiff and sticky. It is caused by the absence of an enzyme called hexosaminidase A or hex A.