The findings, however, were not correlated to testosterone, perhaps lending to the theory of impaired cerebral motor function as an etiological factor for decreased muscle tone in KS boys 72 The prevalence based on postnatal examination, however, was much lower, and for the entire study period from toonly 28 KS males perwere detected, which illustrates low diagnostic yield in the beginning of the 20th century.
Rarely, other cells may have additional chromosome abnormalities.
Personal tools Talk Contributions Log in. Clearly, there are not only females who are XX and males who are XY, but rather, there is a range of chromosome complements, hormone balances, and phenotypic variations that determine sex.
Help Learn to edit Community portal Two sex chromosomes disorders in Derby changes Upload file. This is because even the flowering plant subset has a variety of mating systems. Disorders of the sex chromosomes are also common.
Social behavior and autism traits in a sex chromosomal disorder: Klinefelter 47XXY syndrome. Therefore, we see a pressing need for longitudinal evaluation of the effect of testosterone therapy on a broad range of measures, also including measures of QoL and socioeconomy. Adv Pediatr.
This study also found evidence that having KS is in itself associated with poorer life quality Affected boys often have learning disabilities, resulting in mild delays two sex chromosomes disorders in Derby speech and language development and problems with reading. In our latest published analysis, we have estimated that mortality among KS males is increased with a hazard ratio HR of 1.
Controversially, another study of 89 KS boys aged 7.
However, it also seems that testosterone treatment in KS could be increasing triglyceride levels. Questionnaires and clinical studies have shown that many KS males are underemployed, unemployed, or on disability pensions , , , Other studies have also found increased weight, waist circumference 32 , , and total fat percentage 32 in KS males compared with controls.
Nuclear organization in human sperm: preliminary evidence for altered sex chromosome centromere position in infertile males. Tesarik, J.